| Project Detail |
A robust and sustainable bioeconomy can only be realized through the industrial-scale, carbon-neutral synthesis of fuels, chemicals, and materials. Biofuels, along with a growing number of other sustainable products, are made almost exclusively via fermentation, the age-old technology used to produce foods such as wine, beer, and cheese. Current commercial methods to produce ethanol biofuel from sugar or starches waste more than 30% of the carbon in the feedstock as carbon dioxide (CO2) in the fermentation step alone. This waste limits product yields and squanders valuable feedstock carbon as greenhouse gas CO2. Preventing the loss of carbon as CO2 during bioconversion, or directly incorporating external CO2 as a feedstock into bioconversions, would revolutionize bioprocessing by increasing the product yield per unit of carbon input by more than 50%.
Project Innovation + Advantages:
The University of California, Irvine, proposes a cell-free enzymatic process as the first biological platform to convert carboxylic acids into a broad range of fuels and commodities with greater than 100% carbon efficiency. This is achieved using stabler bioenergy-storage and transmission molecules and specially engineered enzymes. Natural biological pathways for carboxylic acid conversion suffer from a low carbon yield, however. Compared with grain-derived sugars, this project allows carboxylic acids to be produced in large quantities from food and industrial wastes, serving as a more scalable and economical feedstock for biofuel and biochemical production. Scale-up and commercialization of the University of California, Irvine’s transformative cell-free technology will directly enable generation of high-value bioproducts less dependent on cell growth.
Potential Impact:
The application of biology to sustainable uses of waste carbon resources for the generation of energy, intermediates, and final products---i.e., supplanting the “bioeconomy”—provides economic, environmental, social, and national security benefits and offers a promising means of carbon management. |
