Project Detail |
Advanced research for pluripotency Pluripotency allows for a cell to develop into the three primary germ cell layers of the early embryo but not the extra-embryonic tissues. The EU-funded PLASTINET project aims to establish elusive chimera-competent embryonic stem cells from species of importance for research, biomedical applications and livestock improvement. The project hopes to obtain fresh insight into the molecular logic governing early development, lineage plasticity, pluripotent identity and stem cell self-renewal. Researchers will examine human and non-human primates, farm animals in which embryos undergo extended development before implantation, and a marsupial in which pluripotent cells are generated from the trophoblast. |