Project Detail |
From garbage disposal to therapy delivery, exosomes have earned their spot in the limelight
Cells have long been known to move molecules within the cell and to expel them using membrane-bound vesicles. For years, extracellular vesicles were thought to be a cell’s way of putting out the trash and were largely ignored. Within the last 15 years, interest in exosomes has exploded as their critical role in cell-cell communication and the spread of diseases has been recognised. TEXAD is investigating the use of preconditioned exosomes induced to carry regeneration-promoting, anti-inflammatory and immunomodulatory molecules as potential therapies for autoimmune diseases. An innovative exosome-based platform could harness exosome potential for millions of patients with debilitating diseases including rheumatoid arthritis, lupus, inflammatory bowel disease, multiple sclerosis, and type 1 diabetes mellitus. |