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Tenders are invited for Fushun Women's and Children's Hospital Expansion Business Building Construction Project-Equipment Equipment-Mass Spectrometer Fushun City Women and Children's Hospital Expansion Business Housing Construction Project - Equipment Equipment - Mass Spectrometer Fushun City Women and Children's Hospital Expansion Business Housing Construction Project - Equipment Equipment - Mass Spectrometer Tender Notice Local bidding news: Fushun Women's and Children's Hospital Expansion Business Building Construction Project-Equipment Equipment-Mass Spectrometer Tender Announcement official news Announcement title: Fushun Women's and Children's Hospital Expansion Business Building Construction Project-Equipment Equipment-Mass Spectrometer Tender Announcement Validity period: 2022-01-05 to 2022-01-12 Writing unit: Fushun Zhiheng Bidding Service Co., Ltd. (Fushun Women's and Children's Hospital Expansion Business Housing Construction Project-Equipment and Equipment-Mass Spectrometer) Tender Announcement Project Overview Potential suppliers of the Fushun Women’s and Children’s Hospital Expansion Business Building Construction Project-Equipment Equipment-Mass Spectrometer Tender Project should obtain the bidding documents from the Liaoning Government Procurement Network, and before 10:00, January 26, 2022 (Beijing time) Submit bid documents. 1. Basic situation of the project Item Number: JH21-210400-00474 Project Name: Fushun Women's and Children's Hospital Expansion Business Housing Construction Project-Equipment and Equipment-Mass Spectrometer Package number: 001 Budget amount (yuan): 2,500,000.00 Maximum price (yuan): 2,500,000.00 Purchasing requirements: view High performance liquid chromatography triple quadrupole mass spectrometer: 1 unit 1. Equipment requirements ★ 1.1A set of high performance liquid chromatography triple quadrupole mass spectrometer and supporting equipment, priority is given to domestic equipment. It is mainly used for various precision medical testing items such as vitamin testing, biomarkers, endocrine hormones, neonatal genetic metabolic disease screening, bile acid testing, unsaturated fatty acid, blood drug concentration monitoring, etc. 2. Technical requirements 2.1 Performance requirements of quadrupole tandem mass spectrometer ★ 2.1.1 Mass range : covering . 19 - 2800 AMU or wider 2.1.2 Resolution : Mass spectrum half peak width ≤ 0.6-0.8amu ( FWMH ) 2.1.3 Scanning rate: ≥ 15,000 amu/sec 2.1.4 SRM minimum residence time: ≤ 1ms 2.1.5 Dynamic linear range: ≥ 6 orders of magnitude 2.1.6 Quality stability: ≤± 0.1amu/24hrs 2.1.7 Sensitivity: positive ion mode sensitivity: 1pg reserpine on-column injection volume, MRM analysis measures m/z195 (product ion), m/z609 (precursor ion), signal-to-noise ratio ≥ 10000:1 . Negative ion mode Sensitivity: 1pg chloramphenicol on column, the MRM analysis of measured m / z 152 (daughter ion), m / z 321 (parent ion), signal to noise ratio ≥ 5000:. 1 . 2.1.8 Scanning mode: full scan, selective ion scan, product ion scan, parent ion scan, neutral loss scan, multi-reaction simultaneous monitoring scan 2.2 Ion source: ★ 2.2.1 Equipped with independent, heatable electrospray source (ESI) and atmospheric pressure chemical source (APCI) ion sources. Both ESI and APCI ion sources can be heated to 600 degrees or above to improve the desolvation effect; 2.2.2 The flow rate range of the ion source: the flow rate is 1ul/min ~ 3ml/min without splitting and without loss of sensitivity, which effectively ensures that the liquid phase method can be directly transplanted to mass spectrometry detection 2.2.3 The ion source is equipped with an exhaust gas discharge device to prevent the backflow of gas in the closed ion source cavity, reduce the memory effect and pollution of the ion source, reduce the load of the mechanical pump, extend the use time of the mechanical pump oil, and maintain the test environment To protect the health of staff 2.3 Ion transmission part: ★ 2.3.1 The transmission part of the ion source adopts a cone structure design, which can effectively prevent the decomposition and blockage of the sample caused by thermal cracking and condensation, without capillary tubes, simple maintenance, without vacuum removal, and low cost of use; ★ 2.3.2 Use the pre-quadrupole as the ion focusing guide device, which has strong anti-pollution ability; 2.3.3 Ion source interface adopts backflushing technology, detachable purge stop cone 2.4 Quality analyzer; ★ 2.4.1 The use of high-precision pure Mo material combined with the surface gold-plating process cylindrical quadrupole ensures the best quality shaft stability, and does not require additional temperature control and heating functions; ★ 2.4.2 Q1 quadrupole and Q3 quadrupole have pre-rods, which can better eliminate fringe field effects, and can better realize ion focusing and anti-pollution functions. ★ 2.4.3 Collision cell: adopts linear axial acceleration design to effectively eliminate ion pair crosstalk, ensure high-throughput analysis capability, and avoid the influence of neutral ion interference and fragment ion pairs. 2.4.4 Use nitrogen or argon as collision gas without introducing additional gas. 2.5 Detector: Using electron multiplier as detector, no positive and negative ion discrimination effect, long service life, guarantee long-term data stability Qualitative; 2.6 Performance requirements of high performance liquid chromatograph 2.6.1 Flow rate range: 0.001-10.000mL/min, 0.001mL/min is the increment 2.6.2 Flow rate precision: ≤ 0.05%RSD 2.6.3 Gradient precision: ≤ 0.15%RSD ★ 2.6.4 Maximum infusion pressure: ≥ 9000psi 2.6.5 Autosampler: Injection volume: 0.01-100mL , the minimum step width of 0.01 [mu] L , compatible 96 -well plates 2.6.6 Column thermostat: temperature control range: 5 ℃ -85 ℃ , temperature control accuracy: ± 0.1 ℃ , temperature stability: ± 0.05 ℃ 2.6.7 Cross contamination: <0.002% 2.7 Data processing system: 2.7.1 Fully automatic analysis software for neonatal genetic and metabolic diseases, customized reports through compound database, library search function, speed up data processing and reporting 2.7.2 The same software platform realizes the control of liquid chromatography and mass spectrometry, which can fully guarantee the overall performance of the system and the ease of application, training, maintenance, etc. 2.7.3 It can support all Chinese application software, the analysis menu is flexible, and the operation is convenient; it can be directly connected to the Lis system in one step , which is simple to implement and does not use intermediate software. 2.7.4 The workstation and software have the functions of data collection, data processing, qualitative and quantitative analysis, database establishment, spectral library retrieval, etc., with one-click trigger automatic quantitative data processing and reporting capabilities 3. Requirements for supporting reagents The bidder shall provide reagents that meet the following qualifications and testing indicators: 3.1The original equipment can be fitted with amino acid and carnitine detection kits ( ≥ 16 targets ) , and the reagents have obtained the third category of in vitro diagnostic reagent registration. 3.2The original equipment is equipped with fat-soluble vitamins (vitamin A , 25 -hydroxy vitamin D2 , 25 -hydroxy vitamin D3 , vitamin E , vitamin K ). Water-soluble vitamins (vitamin B1 , vitamin B2 , vitamin B6 , vitamin B9 , vitamin B12 ). Contract performance period: supply, commissioning and installation within 30 days after signing the contract Contents of government procurement policies that need to be implemented: implement policies to promote small and medium-sized enterprises, promote employment of the disabled, support prison enterprises, support poverty alleviation and other related policies This project (yes/no) accepts consortium bidding: No 2. Qualification requirements for suppliers 1. Meet the requirements of Article 22 of the "People's Republic of China Government Procurement Law". 2. Qualification requirements to be met to implement government procurement policies: implement policies to promote small and medium-sized enterprises, promote employment of the disabled, support prison enterprises, support poverty alleviation and other related policies 3. Specific qualification requirements for this project: (1) The bidder must have the medical device production or operation certification document approved by the drug regulatory authority, and within the validity period; (2) Have the medical device registration record of the invested product approved by the drug regulatory authority Proof documents, and within the validity period; Third, the warehousing instructions for government procurement suppliers If the suppliers participating in the Liaoning Provincial Government Procurement Activities have not entered the Liaoning Provincial Government Procurement Supplier Database, please read the relevant regulations of "Government Procurement Supplier Storage" published in the "Homepage—Policies and Regulations" of the Liaoning Government Procurement Network, and handle them in a timely manner Warehousing registration procedures. Fill in brief information such as the unit name, unified social credit code, and contact person. After the account is automatically opened by the system, you can participate in government procurement activities. For specific regulations, please refer to the "Notice on Further Optimizing the Storage Procedures of Liaoning Provincial Government Procurement Suppliers" (Liao Cai Cai Han [2020] No. 198). 4. Obtaining bidding documents Time: 08:30 on January 5, 2022 to 16:30 on January 12, 2022 (Beijing time, except statutory holidays) Location: Liaoning Government Procurement Network Method: online
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