Expression of Interest For Vitro Intrinsic Hepatic Clearance And Plasma Protein Binding Studies For Protocol ... in Belgium

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Expression Of Interest For Vitro Intrinsic Hepatic Clearance And Plasma Protein Binding Studies For Protocol Optimisation. Description: The Present Study Aims To Implement Two In Vitro Adme Methods For The Determination Of Intrinsic Hepatic Clearance And Plasma Protein Binding (Ppb), And To Generate High-Quality Experimental Data For A Defined Set Of Selected Chemicals In Accordance With The Jrc-Provided Standard Operating Procedures (Sops). The Primary Objective Is To Produce Robust And Reliable In Vitro Adme Data Using These Two Assays Under Controlled And Harmonised Laboratory Conditions. The Jrc-Provided Sops Serve As The Methodological Foundation Of The Study, And All Critical Procedural Components Necessary For Assay Integrity And Data Quality Must Be Adhered To. A Secondary Objective Is To Perform A Critical Assessment Of The Laboratory-Specific Implementation Of The Sops Within The TendererS Facilities. Start Date For Expression Of Interest: 16/07/2026 Europe/Brussels Deadline For Expression Of Interest: 04/08/2026 03:29 Europe/Rome Tender Link : Https://Ec.Europa.Eu/Info/Funding-Tenders/Opportunities/Portal/Screen/Opportunities/Tender-Details/2B02bf9b-79C9-47Dc-A632-B21f5ad6d955-Exa

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